The Staybridge makes a nice alternative to the massive resorts and theme hotels. It's an all-suites hotel, but the rooms are more like apartments with all the comforts of home with a full kitchen, bedroom, living room and even a washing machine.
It's away from the strip, but the hotel does have a free shuttle there every hour. There was some noise from the planes flying overhead, but it didn't keep me up.
The included breakfast was pretty good too. I'd definitely stay here again or recommend it to a friend (as long as you don't mind being away from the casinos).